All PI3Kinase signaling is not mTOR: dissecting mTOR-dependent and independent signaling pathways in T cells

The mechanistic target of rapamycin (mTOR) is emerging as playing a central role in regulating T cell activation, differentiation, and function. mTOR integrates diverse signals from the immune microenvironment to shape the outcome of T cell receptor (TCR) antigen recognition. Phosphatidylinositol 3-...

Descripción completa

Detalles Bibliográficos
Autores principales: Gamper, Christopher J., Powell, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466461/
https://www.ncbi.nlm.nih.gov/pubmed/23087689
http://dx.doi.org/10.3389/fimmu.2012.00312