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All PI3Kinase signaling is not mTOR: dissecting mTOR-dependent and independent signaling pathways in T cells
The mechanistic target of rapamycin (mTOR) is emerging as playing a central role in regulating T cell activation, differentiation, and function. mTOR integrates diverse signals from the immune microenvironment to shape the outcome of T cell receptor (TCR) antigen recognition. Phosphatidylinositol 3-...
Autores principales: | Gamper, Christopher J., Powell, Jonathan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466461/ https://www.ncbi.nlm.nih.gov/pubmed/23087689 http://dx.doi.org/10.3389/fimmu.2012.00312 |
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