Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor

Taltirelin (TAL) is a thyrotropin-releasing hormone (TRH) analog that is approved for use in humans in Japan. In this study, we characterized TAL binding to and signaling by the human TRH receptor (TRH-R) in a model cell system. We found that TAL exhibited lower binding affinities than TRH and lower...

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Detalles Bibliográficos
Autores principales: Thirunarayanan, Nanthakumar, Raaka, Bruce M., Gershengorn, Marvin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466466/
https://www.ncbi.nlm.nih.gov/pubmed/23087672
http://dx.doi.org/10.3389/fendo.2012.00120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466466/
https://www.ncbi.nlm.nih.gov/pubmed/23087672
http://dx.doi.org/10.3389/fendo.2012.00120

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