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Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor

Taltirelin (TAL) is a thyrotropin-releasing hormone (TRH) analog that is approved for use in humans in Japan. In this study, we characterized TAL binding to and signaling by the human TRH receptor (TRH-R) in a model cell system. We found that TAL exhibited lower binding affinities than TRH and lower...

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Detalles Bibliográficos
Autores principales:	Thirunarayanan, Nanthakumar, Raaka, Bruce M., Gershengorn, Marvin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466466/ https://www.ncbi.nlm.nih.gov/pubmed/23087672 http://dx.doi.org/10.3389/fendo.2012.00120

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