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Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFβ signaling and defects in the Hippo signaling cascade

Malignant mesothelioma (MM) is a neoplasm that arises from serosal surfaces of the pleural, peritoneal and pericardial cavities with worldwide incidence, much of which is caused by asbestos exposure. Patients suffer from pain and dyspnea due to direct invasion of the chest wall, lungs and vertebral...

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Detalles Bibliográficos
Autores principales: Fujii, Makiko, Nakanishi, Hayao, Toyoda, Takeshi, Tanaka, Ichidai, Kondo, Yutaka, Osada, Hirotaka, Sekido, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466546/
https://www.ncbi.nlm.nih.gov/pubmed/22918238
http://dx.doi.org/10.4161/cc.21397