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Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFβ signaling and defects in the Hippo signaling cascade
Malignant mesothelioma (MM) is a neoplasm that arises from serosal surfaces of the pleural, peritoneal and pericardial cavities with worldwide incidence, much of which is caused by asbestos exposure. Patients suffer from pain and dyspnea due to direct invasion of the chest wall, lungs and vertebral...
Autores principales: | Fujii, Makiko, Nakanishi, Hayao, Toyoda, Takeshi, Tanaka, Ichidai, Kondo, Yutaka, Osada, Hirotaka, Sekido, Yoshitaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466546/ https://www.ncbi.nlm.nih.gov/pubmed/22918238 http://dx.doi.org/10.4161/cc.21397 |
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