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Distinct Mechanisms of Calmodulin Binding and Regulation of Adenylyl Cyclases 1 and 8
[Image: see text] Calmodulin (CaM), by mediating the stimulation of the activity of two adenylyl cyclases (ACs), plays a key role in integrating the cAMP and Ca(2+) signaling systems. These ACs, AC1 and AC8, by decoding discrete Ca(2+) signals can contribute to fine-tuning intracellular cAMP dynamic...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466776/ https://www.ncbi.nlm.nih.gov/pubmed/22971080 http://dx.doi.org/10.1021/bi300646y |