Mechanism of Feedback Allosteric Inhibition of ATP Phosphoribosyltransferase

[Image: see text] MtATP-phosphoribosyltransferase catalyzes the first and committed step in l-histidine biosynthesis in Mycobacterium tuberculosis and is therefore subjected to allosteric feedback regulation. Because of its essentiality, this enzyme is being studied as a potential target for novel a...

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Detalles Bibliográficos
Autores principales: Pedreño, Sònia, Pisco, João Pedro, Larrouy-Maumus, Gérald, Kelly, Geoff, de Carvalho, Luiz Pedro Sório
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466779/
https://www.ncbi.nlm.nih.gov/pubmed/22989207
http://dx.doi.org/10.1021/bi300808b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466779/
https://www.ncbi.nlm.nih.gov/pubmed/22989207
http://dx.doi.org/10.1021/bi300808b

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