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Mechanism of Feedback Allosteric Inhibition of ATP Phosphoribosyltransferase
[Image: see text] MtATP-phosphoribosyltransferase catalyzes the first and committed step in l-histidine biosynthesis in Mycobacterium tuberculosis and is therefore subjected to allosteric feedback regulation. Because of its essentiality, this enzyme is being studied as a potential target for novel a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466779/ https://www.ncbi.nlm.nih.gov/pubmed/22989207 http://dx.doi.org/10.1021/bi300808b |