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Probing hybridization parameters from microarray experiments: nearest-neighbor model and beyond

In this article, it is shown how optimized and dedicated microarray experiments can be used to study the thermodynamics of DNA hybridization for a large number of different conformations in a highly parallel fashion. In particular, free energy penalties for mismatches are obtained in two independent...

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Detalles Bibliográficos
Autores principales: Hadiwikarta, W. W., Walter, J.-C., Hooyberghs, J., Carlon, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467032/
https://www.ncbi.nlm.nih.gov/pubmed/22661582
http://dx.doi.org/10.1093/nar/gks475