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Probing hybridization parameters from microarray experiments: nearest-neighbor model and beyond
In this article, it is shown how optimized and dedicated microarray experiments can be used to study the thermodynamics of DNA hybridization for a large number of different conformations in a highly parallel fashion. In particular, free energy penalties for mismatches are obtained in two independent...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467032/ https://www.ncbi.nlm.nih.gov/pubmed/22661582 http://dx.doi.org/10.1093/nar/gks475 |