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Fidelity of capture-enrichment for mtDNA genome sequencing: influence of NUMTs

Enriching target sequences in sequencing libraries via capture hybridization to bait/probes is an efficient means of leveraging the capabilities of next-generation sequencing for obtaining sequence data from target regions of interest. However, homologous sequences from non-target regions may also b...

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Detalles Bibliográficos
Autores principales: Li, Mingkun, Schroeder, Roland, Ko, Albert, Stoneking, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467033/
https://www.ncbi.nlm.nih.gov/pubmed/22649055
http://dx.doi.org/10.1093/nar/gks499