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Customized optimization of metabolic pathways by combinatorial transcriptional engineering

A major challenge in metabolic engineering and synthetic biology is to balance the flux of an engineered heterologous metabolic pathway to achieve high yield and productivity in a target organism. Here, we report a simple, efficient and programmable approach named ‘customized optimization of metabol...

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Detalles Bibliográficos
Autores principales: Du, Jing, Yuan, Yongbo, Si, Tong, Lian, Jiazhang, Zhao, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467037/
https://www.ncbi.nlm.nih.gov/pubmed/22718979
http://dx.doi.org/10.1093/nar/gks549