Spi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemia

Acute leukemias are characterized by deregulation of transcriptional networks that control the lineage specificity of gene expression. The aberrant overexpression of the Spi-1/PU.1 transcription factor leads to erythroleukemia. To determine how Spi-1 mechanistically influences the transcriptional pr...

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Detalles Bibliográficos
Autores principales: Ridinger-Saison, Maya, Boeva, Valentina, Rimmelé, Pauline, Kulakovskiy, Ivan, Gallais, Isabelle, Levavasseur, Benjamin, Paccard, Caroline, Legoix-Né, Patricia, Morlé, François, Nicolas, Alain, Hupé, Philippe, Barillot, Emmanuel, Moreau-Gachelin, Françoise, Guillouf, Christel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467057/
https://www.ncbi.nlm.nih.gov/pubmed/22790984
http://dx.doi.org/10.1093/nar/gks659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467057/
https://www.ncbi.nlm.nih.gov/pubmed/22790984
http://dx.doi.org/10.1093/nar/gks659

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