Cargando…

Kinetics of endogenous mouse FEN1 in base excision repair

The structure specific flap endonuclease 1 (FEN1) plays an essential role in long-patch base excision repair (BER) and in DNA replication. We have generated a fluorescently tagged FEN1 expressing mouse which allows monitoring the localization and kinetics of FEN1 in response to DNA damage in living...

Descripción completa

Detalles Bibliográficos
Autores principales: Kleppa, Liv, Mari, Pierre-Olivier, Larsen, Elisabeth, Lien, Guro Flor, Godon, Camille, Theil, Arjan F., Nesse, Gaute J., Wiksen, Hege, Vermeulen, Wim, Giglia-Mari, Giuseppina, Klungland, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467068/
https://www.ncbi.nlm.nih.gov/pubmed/22810208
http://dx.doi.org/10.1093/nar/gks673