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The CR3 motif of Rrp44p is important for interaction with the core exosome and exosome function

The 10-subunit RNA exosome is involved in a large number of diverse RNA processing and degradation events in eukaryotes. These reactions are carried out by the single catalytic subunit, Rrp44p/Dis3p, which is composed of three parts that are conserved throughout eukaryotes. The exosome is named for...

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Detalles Bibliográficos
Autores principales: Schaeffer, Daneen, Reis, Filipa Pereira, Johnson, Sean J., Arraiano, Cecília Maria, van Hoof, Ambro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467083/
https://www.ncbi.nlm.nih.gov/pubmed/22833611
http://dx.doi.org/10.1093/nar/gks693