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An RNA Interference Lethality Screen of the Human Druggable Genome to Identify Molecular Vulnerabilities in Epithelial Ovarian Cancer

Targeted therapies have been used to combat many tumor types; however, few have effectively improved the overall survival in women with epithelial ovarian cancer, begging for a better understanding of this deadly disease and identification of essential drivers of tumorigenesis that can be targeted e...

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Detalles Bibliográficos
Autores principales: Sethi, Geetika, Pathak, Harsh B., Zhang, Hong, Zhou, Yan, Einarson, Margret B., Vathipadiekal, Vinod, Gunewardena, Sumedha, Birrer, Michael J., Godwin, Andrew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467214/
https://www.ncbi.nlm.nih.gov/pubmed/23056589
http://dx.doi.org/10.1371/journal.pone.0047086