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An RNA Interference Lethality Screen of the Human Druggable Genome to Identify Molecular Vulnerabilities in Epithelial Ovarian Cancer
Targeted therapies have been used to combat many tumor types; however, few have effectively improved the overall survival in women with epithelial ovarian cancer, begging for a better understanding of this deadly disease and identification of essential drivers of tumorigenesis that can be targeted e...
Autores principales: | Sethi, Geetika, Pathak, Harsh B., Zhang, Hong, Zhou, Yan, Einarson, Margret B., Vathipadiekal, Vinod, Gunewardena, Sumedha, Birrer, Michael J., Godwin, Andrew K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467214/ https://www.ncbi.nlm.nih.gov/pubmed/23056589 http://dx.doi.org/10.1371/journal.pone.0047086 |
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