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Fusion Toxin BLyS-Gelonin Inhibits Growth of Malignant Human B Cell Lines In Vitro and In Vivo

B lymphocyte stimulator (BLyS) is a member of the TNF superfamily of cytokines. The biological activity of BLyS is mediated by three cell surface receptors: BR3/BAFF-R, TACI and BCMA. The expression of these receptors is highly restricted to B cells, both normal and malignant. A BLyS-gelonin fusion...

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Detalles Bibliográficos
Autores principales: Luster, Troy A., Mukherjee, Ipsita, Carrell, Jeffrey A., Cho, Yun Hee, Gill, Jeffrey, Kelly, Lizbeth, Garcia, Andy, Ward, Christopher, Oh, Luke, Ullrich, Stephen J., Migone, Thi-Sau, Humphreys, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467252/
https://www.ncbi.nlm.nih.gov/pubmed/23056634
http://dx.doi.org/10.1371/journal.pone.0047361