Regulation of the CCL2 Gene in Pancreatic β-Cells by IL-1β and Glucocorticoids: Role of MKP-1

Release of pro-inflammatory cytokines from both resident and invading leukocytes within the pancreatic islets impacts the development of Type 1 diabetes mellitus. Synthesis and secretion of the chemokine CCL2 from pancreatic β-cells in response to pro-inflammatory signaling pathways influences immun...

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Detalles Bibliográficos
Autores principales: Burke, Susan J., Goff, Matthew R., Updegraff, Barrett L., Lu, Danhong, Brown, Patricia L., Minkin, Steven C., Biggerstaff, John P., Zhao, Ling, Karlstad, Michael D., Collier, J. Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467264/
https://www.ncbi.nlm.nih.gov/pubmed/23056550
http://dx.doi.org/10.1371/journal.pone.0046986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467264/
https://www.ncbi.nlm.nih.gov/pubmed/23056550
http://dx.doi.org/10.1371/journal.pone.0046986

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