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Human Langerhans Cells Control Th Cells via Programmed Death-Ligand 1 in Response to Bacterial Stimuli and Nickel-Induced Contact Allergy

Langerhans cells (LCs) are suspected to initiate inflammatory immune responses to contact allergens and pathogenic bacteria. In chronic infectious diseases, programmed death ligand (PD-L) 1 exhibits both inhibitory and costimulatory functions on T cell-mediated activation and tolerance. Here, we inv...

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Detalles Bibliográficos
Autores principales: Hitzler, Manuel, Majdic, Otto, Heine, Guido, Worm, Margitta, Ebert, Grit, Luch, Andreas, Peiser, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467287/
https://www.ncbi.nlm.nih.gov/pubmed/23056446
http://dx.doi.org/10.1371/journal.pone.0046776