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Activation of Akt/protein kinase B mediates the protective effects of mechanical stretching against myocardial ischemia-reperfusion injury

Akt/protein kinase B is a well-known cell survival factor and activated by many stimuli including mechanical stretching. Therefore, we evaluated the cardioprotective effect of a brief mechanical stretching of rat hearts and determined whether activation of Akt through phosphatidylinositol 3-kinase (...

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Detalles Bibliográficos
Autores principales: Kim, Chan-Hyung, Hao, Jia, Ahn, Hee-Yul, Kim, Si Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467398/
https://www.ncbi.nlm.nih.gov/pubmed/23000580
http://dx.doi.org/10.4142/jvs.2012.13.3.235