Influence of FCGR3A genotype on the therapeutic response to rituximab in rheumatoid arthritis: an observational cohort study

OBJECTIVES: To determine whether a polymorphism in the Fcγ receptor type IIIA (FCGR3A-F158V), influencing immunoglobulin G binding affinity, relates to the therapeutic efficacy of rituximab in rheumatoid arthritis (RA) patients. DESIGN: Observational cohort study. SETTING: Three university hospital...

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Detalles Bibliográficos
Autores principales: Kastbom, Alf, Cöster, Lars, Ärlestig, Lisbeth, Chatzidionysiou, Aikaterini, van Vollenhoven, Ronald F, Padyukov, Leonid, Rantapää-Dahlqvist, Solbritt, Saevarsdottir, Saedis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2012
Materias:
Rheumatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467642/
https://www.ncbi.nlm.nih.gov/pubmed/23002160
http://dx.doi.org/10.1136/bmjopen-2012-001524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467642/
https://www.ncbi.nlm.nih.gov/pubmed/23002160
http://dx.doi.org/10.1136/bmjopen-2012-001524

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