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Preparation and optimization of microemulsion of rosuvastatin calcium

Due to very less bioavailability (20%) of Rosuvastatin calcium, an attempt was made to develop and optimize microemulsion formulation. Capmul MCM, Tween 20 and PEG 400 were selected as oil, surfactant and cosurfactant respectively as the drug is having higher solubility in them. 3:1% w/w S:CoS was s...

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Detalles Bibliográficos
Autores principales: Patel, Zalak B., Patel, Kruti S., Shah, Ankit S., Surti, Naazneen I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467806/
https://www.ncbi.nlm.nih.gov/pubmed/23066186
http://dx.doi.org/10.4103/0975-7406.94164