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Preparation and optimization of microemulsion of rosuvastatin calcium
Due to very less bioavailability (20%) of Rosuvastatin calcium, an attempt was made to develop and optimize microemulsion formulation. Capmul MCM, Tween 20 and PEG 400 were selected as oil, surfactant and cosurfactant respectively as the drug is having higher solubility in them. 3:1% w/w S:CoS was s...
Autores principales: | Patel, Zalak B., Patel, Kruti S., Shah, Ankit S., Surti, Naazneen I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467806/ https://www.ncbi.nlm.nih.gov/pubmed/23066186 http://dx.doi.org/10.4103/0975-7406.94164 |
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