Floating microspheres of valacyclovir HCl: Formulation, optimization, characterization, in vitro and in vivo floatability studies

Floating microspheres are multiple unit Gastroretentive drug delivery systems. Valacyclovir hydrochloride (VCH) is L-valyl ester prodrug of acyclovir. VCH degrades in intestinal fluid. The objective was to develop floating microspheres of VCH to localise the drug at upper part of GIT, for improved a...

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Detalles Bibliográficos
Autores principales: Goswami, Nilamgiri, Joshi, Garima, Sawant, Krutika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Original/Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467807/
https://www.ncbi.nlm.nih.gov/pubmed/23066217
http://dx.doi.org/10.4103/0975-7406.94118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467807/
https://www.ncbi.nlm.nih.gov/pubmed/23066217
http://dx.doi.org/10.4103/0975-7406.94118

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