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Dissolution enhancement of albendazole through nanocrystal formulation

Albendazole, a BCS class II drug, has poor dissolution characteristic. In order to enhance dissolution nanocrystals were prepared by antisolvent precipitation process using PVP K-30(0.05%,0.1%,0.2%,0.4%) as stabilizer. The process was optimized in terms of concentration of stabilizer(PVP K 30) in or...

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Detalles Bibliográficos
Autores principales: Koradia, D. Krishna, Parikh, H. Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467808/
https://www.ncbi.nlm.nih.gov/pubmed/23066210
http://dx.doi.org/10.4103/0975-7406.94141