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LC-MS/MS Identification of a Bromelain Peptide Biomarker from Ananas comosus Merr

Bromelain (Br) is a cysteine peptidase (GenBank AEH26024.1) from pineapple, with over 40 years of clinical use. The constituents mediating its anti-inflammatory activity are not thoroughly characterized and no peptide biomarker exists. Our objective is to characterize Br raw material and identify pe...

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Detalles Bibliográficos
Autores principales: Secor, Eric R., Szczepanek, Steven M., Singh, Anurag, Guernsey, Linda, Natarajan, Prabitha, Rezaul, Karim, Han, David K., Thrall, Roger S., Silbart, Lawrence K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467939/
https://www.ncbi.nlm.nih.gov/pubmed/23082082
http://dx.doi.org/10.1155/2012/548486