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A new solid oral tablet formulation of posaconazole: a randomized clinical trial to investigate rising single- and multiple-dose pharmacokinetics and safety in healthy volunteers

OBJECTIVES: Posaconazole is an extended-spectrum triazole with proven efficacy as antifungal treatment and prophylaxis. The marketed oral suspension should be taken with food to maximize systemic absorption. A new solid oral tablet has been developed with improved bioavailability that can be adminis...

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Detalles Bibliográficos
Autores principales: Krishna, G., Ma, L., Martinho, M., Preston, R. A., O'Mara, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468079/
https://www.ncbi.nlm.nih.gov/pubmed/22833639
http://dx.doi.org/10.1093/jac/dks268