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Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines

BACKGROUND: Integrase defective lentiviral vectors (IDLV) represent a promising delivery system for immunization purposes. Human dendritic cells (DC) are the main cell types mediating the immune response and are readily transduced by IDLV, allowing effective triggering of in vitro expansion of antig...

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Detalles Bibliográficos
Autores principales: Negri, Donatella RM, Rossi, Alessandra, Blasi, Maria, Michelini, Zuleika, Leone, Pasqualina, Chiantore, Maria Vincenza, Baroncelli, Silvia, Perretta, Gemma, Cimarelli, Andrea, Klotman, Mary E, Cara, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468359/
https://www.ncbi.nlm.nih.gov/pubmed/22913641
http://dx.doi.org/10.1186/1742-4690-9-69