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Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines
BACKGROUND: Integrase defective lentiviral vectors (IDLV) represent a promising delivery system for immunization purposes. Human dendritic cells (DC) are the main cell types mediating the immune response and are readily transduced by IDLV, allowing effective triggering of in vitro expansion of antig...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468359/ https://www.ncbi.nlm.nih.gov/pubmed/22913641 http://dx.doi.org/10.1186/1742-4690-9-69 |