Pharmacodynamic analysis of tumour perfusion assessed by (15)O-water-PET imaging during treatment with sunitinib malate in patients with advanced malignancies

BACKGROUND: We evaluated pharmacodynamic changes in tumour perfusion using positron emission tomography (PET) imaging with (15)O-water to assess biological response to sunitinib, a multitargeted tyrosine kinase inhibitor. METHODS: Patients with advanced malignancies received sunitinib 50 mg/day oral...

Descripción completa

Detalles Bibliográficos
Autores principales: Scott, Andrew M, Mitchell, Paul L, O'Keefe, Graeme, Saunder, Timothy, Hicks, Rodney J, Poon, Aurora, Baum, Charles, Brega, Nicoletta, McCarthy, Timothy J, Toner, Guy C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468361/
https://www.ncbi.nlm.nih.gov/pubmed/22682364
http://dx.doi.org/10.1186/2191-219X-2-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468361/
https://www.ncbi.nlm.nih.gov/pubmed/22682364
http://dx.doi.org/10.1186/2191-219X-2-31

Ejemplares similares