Heterologous expression of human costimulatory molecule B7-2 and construction of B7-2 immobilized polyhydroxyalkanoate nanoparticles for use as an immune activation agent

BACKGROUND: Costimulation of T cells via costimulatory molecules such as B7 is important for eliciting cell-mediated antitumor immunity. Presenting costimulation molecules by immobilizing recombinant B7 on the surface of nanovectors is a novel strategy for complementary therapy. Polyhydroxyalkanoate...

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Detalles Bibliográficos
Autores principales: Li, Ming-Chuan, Liu, Qian-Qian, Lu, Xiao-Yun, Zhang, Ya-Li, Wang, Lei-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468374/
https://www.ncbi.nlm.nih.gov/pubmed/22846711
http://dx.doi.org/10.1186/1472-6750-12-43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468374/
https://www.ncbi.nlm.nih.gov/pubmed/22846711
http://dx.doi.org/10.1186/1472-6750-12-43

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