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Probing the role of stochasticity in a model of the embryonic stem cell – heterogeneous gene expression and reprogramming efficiency

BACKGROUND: Embryonic stem cells (ESC) have the capacity to self-renew and remain pluripotent, while continuously providing a source of a variety of differentiated cell types. Understanding what governs these properties at the molecular level is crucial for stem cell biology and its application to r...

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Detalles Bibliográficos
Autores principales: Chickarmane, Vijay, Olariu, Victor, Peterson, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468383/
https://www.ncbi.nlm.nih.gov/pubmed/22889237
http://dx.doi.org/10.1186/1752-0509-6-98