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Functional Analyses of Complement Convertases Using C3 and C5-Depleted Sera

C3 and C5 convertases are central stages of the complement cascade since they converge the different initiation pathways, augment complement activation by an amplification loop and lead to a common terminal pathway resulting in the formation of the membrane attack complex. Several complement inhibit...

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Detalles Bibliográficos
Autores principales: Okroj, Marcin, Holmquist, Emelie, King, Ben C., Blom, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468486/
https://www.ncbi.nlm.nih.gov/pubmed/23071769
http://dx.doi.org/10.1371/journal.pone.0047245