Cargando…

Functional Analyses of Complement Convertases Using C3 and C5-Depleted Sera

C3 and C5 convertases are central stages of the complement cascade since they converge the different initiation pathways, augment complement activation by an amplification loop and lead to a common terminal pathway resulting in the formation of the membrane attack complex. Several complement inhibit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Okroj, Marcin, Holmquist, Emelie, King, Ben C., Blom, Anna M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468486/ https://www.ncbi.nlm.nih.gov/pubmed/23071769 http://dx.doi.org/10.1371/journal.pone.0047245

Ejemplares similares

Testing the Activity of Complement Convertases in Serum/Plasma for Diagnosis of C4NeF-Mediated C3 Glomerulonephritis
por: Blom, Anna M., et al.
Publicado: (2016)

Mutations resulting in the formation of hyperactive complement convertases support cytocidal effect of anti-CD20 immunotherapeutics
por: Felberg, Anna, et al.
Publicado: (2019)

Plasmin as a complement C5 convertase
por: Leung, Lawrence L., et al.
Publicado: (2016)

Overactivity of Alternative Pathway Convertases in Patients With Complement-Mediated Renal Diseases
por: Michels, Marloes A. H. M., et al.
Publicado: (2018)

In situ Visualization of C3/C5 Convertases to Differentiate Complement Activation
por: Person, Fermin, et al.
Publicado: (2020)

C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3- and C5-Convertases
por: Zhao, Fei, et al.
Publicado: (2019)

Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes
por: Berends, Evelien T. M., et al.
Publicado: (2015)

Covalent association of C3b with C4b within C5 convertase of the classical complement pathway
Publicado: (1987)

Alternative pathway of complement: recruitment of precursor properdin by the labile C3/C5 convertase and the potentiation of the pathway
Publicado: (1976)

Proprotein Convertases and the Complement System
por: Dobó, József, et al.
Publicado: (2022)

Cartilage oligomeric matrix protein-induced complement activation in systemic sclerosis
por: Otteby, Kaisa E, et al.
Publicado: (2013)

The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients
por: Englund, Emelie, et al.
Publicado: (2015)

Inhibition of C3 Convertase Activity by Hepatitis C Virus as an Additional Lesion in the Regulation of Complement Components
por: Kim, Hangeun, et al.
Publicado: (2014)

IN VITRO STUDIES OF COMPLEMENT FUNCTION IN SERA OF C4-DEFICIENT GUINEA PIGS
por: Frank, Michael M., et al.
Publicado: (1971)

Bacterial killing by complement requires membrane attack complex formation via surface‐bound C5 convertases
por: Heesterbeek, Dani AC, et al.
Publicado: (2019)

Editorial: Complement and Immunotherapeutics
por: Okrój, Marcin, et al.
Publicado: (2021)

Analysis of complement biomarkers in systemic sclerosis indicates a distinct pattern in scleroderma renal crisis
por: Okrój, Marcin, et al.
Publicado: (2016)

THE SECOND COMPONENT OF HUMAN COMPLEMENT: ITS ISOLATION, FRAGMENTATION BY C'1 ESTERASE, AND INCORPORATION INTO C'3 CONVERTASE
por: Polley, Margaret J., et al.
Publicado: (1968)

In Silico Designed Gain-of-Function Variants of Complement C2 Support Cytocidal Activity of Anticancer Monoclonal Antibodies
por: Urban, Aleksandra, et al.
Publicado: (2022)

MHC Class III products: an electron microscopic study of the C3 convertases of human complement
Publicado: (1984)

Modulation of the formation of the amplification convertase of complement, C3b, Bb, by native and commercial heparin
Publicado: (1978)

Complement C4d-specific antibodies for the diagnosis of lung cancer
por: Ajona, Daniel, et al.
Publicado: (2017)

Structural and functional implications of the complement convertase stabilized by a staphylococcal inhibitor
por: Rooijakkers, Suzan H M, et al.
Publicado: (2009)

Staphylococcal complement evasion by various convertase-blocking molecules
por: Jongerius, Ilse, et al.
Publicado: (2007)

Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein
por: Urban, Aleksandra, et al.
Publicado: (2021)

C5a elevation in convalescents from severe COVID-19 is not associated with early complement activation markers C3bBbP or C4d
por: Kowalska, Daria, et al.
Publicado: (2022)

Complement Activation as a Helping Hand for Inflammophilic Pathogens and Cancer
por: Okrój, Marcin, et al.
Publicado: (2019)

Editorial: Expert opinions and perspectives in complement: 2022
por: Okrój, Marcin, et al.
Publicado: (2023)

The complement system is activated in synovial fluid from subjects with knee injury and from patients with osteoarthritis
por: Struglics, André, et al.
Publicado: (2016)

INTERACTIONS OF C-REACTIVE PROTEIN WITH THE COMPLEMENT SYSTEM : I. PROTAMINE-INDUCED CONSUMPTION OF COMPLEMENT IN ACUTE PHASE SERA
por: Siegel, Joan, et al.
Publicado: (1974)

The Sez6 Family Inhibits Complement by Facilitating Factor I Cleavage of C3b and Accelerating the Decay of C3 Convertases
por: Qiu, Wen Q., et al.
Publicado: (2021)

Functional Characterization of Alternative and Classical Pathway C3/C5 Convertase Activity and Inhibition Using Purified Models
por: Zwarthoff, Seline A., et al.
Publicado: (2018)

Requirements for the solubilization of immune aggregates by complement: assembly of a factor B-dependent C3-convertase on the immune complexes
Publicado: (1977)

Substitutions at position 263 within the von Willebrand factor type A domain determine the functionality of complement C2 protein
por: Kuźniewska, Alicja, et al.
Publicado: (2022)

Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System
por: Pedersen, Dennis V., et al.
Publicado: (2019)

Monitoring of the Complement System Status in Patients With B-Cell Malignancies Treated With Rituximab
por: Felberg, Anna, et al.
Publicado: (2020)

Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3
Publicado: (1981)

C3 PROACTIVATOR CONVERTASE AND ITS MODE OF ACTION
por: Müller-Eberhard, Hans J., et al.
Publicado: (1972)

Measuring plasma C4D to monitor immune complexes in lupus nephritis
por: Kraaij, Tineke, et al.
Publicado: (2019)

C4b-Binding Protein Is Present in Affected Areas of Myocardial Infarction during the Acute Inflammatory Phase and Covers a Larger Area than C3
por: Trouw, Leendert A., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_5el1a06cm8vcuola2apja0riho