NF-Y Recruits Both Transcription Activator and Repressor to Modulate Tissue- and Developmental Stage-Specific Expression of Human γ-Globin Gene

The human embryonic, fetal and adult β-like globin genes provide a paradigm for tissue- and developmental stage-specific gene regulation. The fetal γ-globin gene is expressed in fetal erythroid cells but is repressed in adult erythroid cells. The molecular mechanism underlying this transcriptional s...

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Detalles Bibliográficos
Autores principales: Zhu, Xingguo, Wang, Yongchao, Pi, Wenhu, Liu, Hui, Wickrema, Amittha, Tuan, Dorothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468502/
https://www.ncbi.nlm.nih.gov/pubmed/23071749
http://dx.doi.org/10.1371/journal.pone.0047175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468502/
https://www.ncbi.nlm.nih.gov/pubmed/23071749
http://dx.doi.org/10.1371/journal.pone.0047175

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