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Fringe Controls Naïve CD4(+)T Cells Differentiation through Modulating Notch Signaling in Asthmatic Rat Models

The ability of Notch signaling to regulate T helper cell development and differentiation has been widely accepted. Fringe, O-fucose-β1,3-N-acetylglucosaminyltransferases modulate Notch receptor expression and promote the Notch signaling pathway through receptor-ligand binding. In this study, we assa...

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Detalles Bibliográficos
Autores principales: Gu, Wen, Xu, Weiguo, Ding, Tao, Guo, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468515/
https://www.ncbi.nlm.nih.gov/pubmed/23071776
http://dx.doi.org/10.1371/journal.pone.0047288