Pathways Involved in the Synergistic Activation of Macrophages by Lipoteichoic Acid and Hemoglobin

Lipoteichoic acid (LTA) is a Gram-positive cell surface molecule that is found in both a cell-bound form and cell-free form in the host during an infection. Hemoglobin (Hb) can synergize with LTA, a TLR2 ligand, to potently activate macrophage innate immune responses in a TLR2- and TLR4-dependent wa...

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Detalles Bibliográficos
Autores principales: Cox, Kathleen H., Cox, Michelle E., Woo-Rasberry, Virginia, Hasty, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468568/
https://www.ncbi.nlm.nih.gov/pubmed/23071790
http://dx.doi.org/10.1371/journal.pone.0047333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468568/
https://www.ncbi.nlm.nih.gov/pubmed/23071790
http://dx.doi.org/10.1371/journal.pone.0047333

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