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Pathways Involved in the Synergistic Activation of Macrophages by Lipoteichoic Acid and Hemoglobin
Lipoteichoic acid (LTA) is a Gram-positive cell surface molecule that is found in both a cell-bound form and cell-free form in the host during an infection. Hemoglobin (Hb) can synergize with LTA, a TLR2 ligand, to potently activate macrophage innate immune responses in a TLR2- and TLR4-dependent wa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468568/ https://www.ncbi.nlm.nih.gov/pubmed/23071790 http://dx.doi.org/10.1371/journal.pone.0047333 |