A Novel Anticancer Therapy That Simultaneously Targets Aberrant p53 and Notch Activities in Tumors

Notch signaling pathway plays an important role in tumorigenesis by maintaining the activity of self-renewal of cancer stem cells, and therefore, it is hypothesized that interference of Notch signaling may inhibit tumor formation and progression. H101 is a recombinant oncolytic adenovirus that is cy...

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Detalles Bibliográficos
Autores principales: Yao, Yuting, Wang, Li, Zhang, He, Wang, Haibo, Zhao, Xiaoping, Zhang, Yidan, Zhang, Leilei, Fan, Xianqun, Qian, Guanxiang, Hu, Ji-Fan, Ge, Shengfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468572/
https://www.ncbi.nlm.nih.gov/pubmed/23071601
http://dx.doi.org/10.1371/journal.pone.0046627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468572/
https://www.ncbi.nlm.nih.gov/pubmed/23071601
http://dx.doi.org/10.1371/journal.pone.0046627

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