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The Effects of Amino Acid Composition of Glutamine-Rich Domains on Amyloid Formation and Fragmentation
Fragmentation of amyloid polymers by the chaperone Hsp104 allows them to propagate as prions in yeast. The factors which determine the frequency of fragmentation are unclear, though it is often presumed to depend on the physical strength of prion polymers. Proteins with long polyglutamine stretches...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468588/ https://www.ncbi.nlm.nih.gov/pubmed/23071575 http://dx.doi.org/10.1371/journal.pone.0046458 |