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Abnormal Expression of the Pre-mRNA Splicing Regulators SRSF1, SRSF2, SRPK1 and SRPK2 in Non Small Cell Lung Carcinoma

Splicing abnormalities frequently occur in cancer. A key role as splice site choice regulator is played by the members of the SR (Ser/Arg-rich) family of proteins. We recently demonstrated that SRSF2 is involved in cisplatin-mediated apoptosis of human lung carcinoma cell lines. In this study, by us...

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Detalles Bibliográficos
Autores principales: Gout, Stephanie, Brambilla, Elisabeth, Boudria, Asma, Drissi, Romain, Lantuejoul, Sylvie, Gazzeri, Sylvie, Eymin, Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468597/
https://www.ncbi.nlm.nih.gov/pubmed/23071587
http://dx.doi.org/10.1371/journal.pone.0046539