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Beneficial Effect of Antibodies against β- Secretase Cleavage Site of App on Alzheimer’s-Like Pathology in Triple-Transgenic Mice

The toxicity of amyloid β and tau, the two hallmark proteins in Alzheimer’s disease (AD), has been extensively studied individually. Recently new data suggest their possible interactions and synergistic effects in the disease. In this study, we investigate the ability of antibodies against the β sec...

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Detalles Bibliográficos
Autores principales: Rabinovich-Nikitin, Inna, Rakover, Idan S., Becker, Maria, Solomon, Beka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468631/
https://www.ncbi.nlm.nih.gov/pubmed/23071606
http://dx.doi.org/10.1371/journal.pone.0046650