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Improved Inhibitor Screening Experiments by Comparative Analysis of Simulated Enzyme Progress Curves
A difficulty associated with high throughput screening for enzyme inhibitors is to establish reaction conditions that maximize the sensitivity and resolution of the assay. Deduction of information from end-point assays at single concentrations requires a detailed understanding of the time progress o...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468632/ https://www.ncbi.nlm.nih.gov/pubmed/23071631 http://dx.doi.org/10.1371/journal.pone.0046764 |