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Selective and hyperactive uptake of foreign DNA by adaptive immune systems of an archaeon via two distinct mechanisms

Central to the disparate adaptive immune systems of archaea and bacteria are clustered regularly interspaced short palindromic repeats (CRISPR). The spacer regions derive from invading genetic elements and, via RNA intermediates and associated proteins, target and cleave nucleic acids of the invader...

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Detalles Bibliográficos
Autores principales: Erdmann, Susanne, Garrett, Roger A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468723/
https://www.ncbi.nlm.nih.gov/pubmed/22834906
http://dx.doi.org/10.1111/j.1365-2958.2012.08171.x