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Selective and hyperactive uptake of foreign DNA by adaptive immune systems of an archaeon via two distinct mechanisms
Central to the disparate adaptive immune systems of archaea and bacteria are clustered regularly interspaced short palindromic repeats (CRISPR). The spacer regions derive from invading genetic elements and, via RNA intermediates and associated proteins, target and cleave nucleic acids of the invader...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468723/ https://www.ncbi.nlm.nih.gov/pubmed/22834906 http://dx.doi.org/10.1111/j.1365-2958.2012.08171.x |