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Growth conditions and environmental factors impact aerosolization but not virulence of Francisella tularensis infection in mice
In refining methodology to develop a mouse model for inhalation of Francisella tularensis, it was noted that both relative humidity and growth media impacted the aerosol concentration of the live vaccine strain (LVS) of F. tularensis. A relative humidity of less than 55% had a negative impact on the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468843/ https://www.ncbi.nlm.nih.gov/pubmed/23087911 http://dx.doi.org/10.3389/fcimb.2012.00126 |