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Selective Constraint on Human Pre-mRNA Splicing by Protein Structural Properties

Alternative splicing (AS) is a major mechanism of increasing proteome diversity in complex organisms. Different AS transcript isoforms may be translated into peptide sequences of significantly different lengths and amino acid compositions. One important question, then, is how AS is constrained by pr...

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Detalles Bibliográficos
Autores principales: Gelly, Jean-Christophe, Lin, Hsuan-Yu, de Brevern, Alexandre G., Chuang, Trees-Juen, Chen, Feng-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468958/
https://www.ncbi.nlm.nih.gov/pubmed/22936073
http://dx.doi.org/10.1093/gbe/evs071