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Selective Constraint on Human Pre-mRNA Splicing by Protein Structural Properties
Alternative splicing (AS) is a major mechanism of increasing proteome diversity in complex organisms. Different AS transcript isoforms may be translated into peptide sequences of significantly different lengths and amino acid compositions. One important question, then, is how AS is constrained by pr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468958/ https://www.ncbi.nlm.nih.gov/pubmed/22936073 http://dx.doi.org/10.1093/gbe/evs071 |