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Why GPCRs behave differently in cubic and lamellar lipidic mesophases

[Image: see text] Recent successes in the crystallographic determination of structures of transmembrane proteins in the G protein-coupled receptor (GPCR) family have established the lipidic cubic phase (LCP) environment as the medium of choice for growing structure-grade crystals by the method terme...

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Detalles Bibliográficos
Autores principales: Khelashvili, George, Albornoz, Pedro Blecua Carrillo, Johner, Niklaus, Mondal, Sayan, Caffrey, Martin, Weinstein, Harel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469068/
https://www.ncbi.nlm.nih.gov/pubmed/22931253
http://dx.doi.org/10.1021/ja3056485