A Novel Role of IGF1 in Apo2L/TRAIL-Mediated Apoptosis of Ewing Tumor Cells

Insulin-like growth factor 1 (IGF1) reputedly opposes chemotoxicity in Ewing sarcoma family of tumor (ESFT) cells. However, the effect of IGF1 on apoptosis induced by apoptosis ligand 2 (Apo2L)/tumor necrosis factor (TNF-) related apoptosis-inducing ligand (TRAIL) remains to be established. We find...

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Detalles Bibliográficos
Autores principales: van Valen, Frans, Harrer, Henning, Hotfilder, Marc, Dirksen, Uta, Pap, Thomas, Gosheger, George, Humpf, Hans-Ulrich, Jürgens, Heribert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469244/
https://www.ncbi.nlm.nih.gov/pubmed/23091403
http://dx.doi.org/10.1155/2012/782970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469244/
https://www.ncbi.nlm.nih.gov/pubmed/23091403
http://dx.doi.org/10.1155/2012/782970

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